Which UDS measure is more sensitive for cognitive impairment in Parkinson's
disease (PD): WAIS: digit-symbol coding, clock drawing test, cube, the Benson
 
   Lead Investigator:    Thomas Kiely
   Institution      :    Ray Dolby Brain Health Center/CPMC
   E-Mail           :    kielyt1@sutterhealth.org
   Proposal ID      :    750



   Proposal Description:
   Visuospatial, executive functions and processing speed deficits are common in PD. Historically, figure copy tests such as the intersecting pentagons and the Necker cube have shown to predict cognitive decline in PD, with the Necker cube demonstrating greater sensitivity to cognitive impairment. The Uniform Dataset Battery (UDS), however, incorporates a relative paucity of figure copy tests and has only recently included the cube since the UDS v3.0 launch in March 2015. The UDS battery includes tests sensitive to each of these cognitive domains including intersecting pentagons (visuospatial), clock drawing test (executive functions / visuospatial), the Benson Figure Copy, digit-symbol coding (processing speed), and now the cube. The objective of this study is to evaluate which of these UDS tests is most sensitive for cognitive impairment in PD.